NFL power rankings: Eagles, Bills fall behind 49ers, Lions; Patriots, Colts, Broncos leap for Week 6

How do all 32 teams in the NFL stack up against each other coming out of Week 5 of the 2025 NFL regular season? Here’s an updated look from best to worst.

With the 49ers’ Offense Gutted, One Star Must Deliver on TNF

The San Francisco 49ers enter Thursday night’s divisional matchup with the Los Angeles Rams dangerously short-handed. Injuries have severely depleted

Jaguars vs 49ers: How to Watch Week 4

Game time, TV/radio schedule, betting odds, and more for Jaguars vs 49ers in Week 4.

49ers rally to top Cardinals with game-winning field goal, improve to 3-0 behind Mac Jones

Mac Jones replacing Brock Purdy seems to be working out just fine so far in San Francisco.

Brock Purdy says he’s trying to be smart with his body; likely a game time decision for Week 3

Meanwhile, Jauan Jennings missed another practice

49ers QB Brock Purdy returns to practice, could play Sunday against Arizona

San Francisco 49ers quarterback Brock Purdy returned to practice on Wednesday and has a chance to play this week after missing a game with a toe injury. Coach Kyle Shanahan said Purdy would be limited at practice because of the toe and a left shoulder injury but could be healthy enough to suit up Sunday against Arizona. Purdy hurt his toe in the first half of the season opener at Seattle but played through the injury, leading a game-winning touchdown drive capped by a 4-yard pass to Jake Tonges.

49ers’ Christian McCaffrey is 3rd player in NFL history with dual-threat combo record

CMC is the only healthy one.

49ers news: Mac Jones, Christian McCaffrey’s immediate reaction to win over Saints

Mac Jones and Christian McCaffrey sent messages directly to 49ers fans walking off the field after their Week 2 win over the Saints.

Christian McCaffrey Puts Rumors to Rest Giving Final Word on 49ers Calf Injury Concern

Christian McCaffrey was dealing with a calf injury before Week 1, and he noted that it was nothing serious.

49ers Fans Stunned as Kyle Shanahan Delivers Brutal Injury Update on QB Brock Purdy

Well this might be bad.