San Francisco 49ers fans can officially circle their calendars: the Tennessee Titans come to Levi’s Stadium on Sunday, December 14, 2025, in a late-window clash that could further reshape the NFC playoff picture. Kickoff is locked in for 1:25 p.m. Pacific Time in Santa Clara, which lines up as 3:25 p.m. Central and 4:25 p.m. Eastern for viewers across the United States.
The game will be broadcast nationally on FOX, with additional access through NFL+ for mobile and in-market streaming, as well as live TV streaming platforms that carry FOX such as YouTube TV, Fubo and similar services. International 49ers supporters can tune in via their local NFL rightsholders (for example DAZN in Canada or Sky Sports in the U.K.), many of which will carry Week 15 action live or on delay.
Weather for this December showdown looks almost tailor-made for a high-quality game of football. The latest forecast for Santa Clara calls for partly cloudy skies and mild, dry conditions, with temperatures hovering around 59–62°F (15–17°C) at kickoff and climbing toward 65°F (18°C) later in the afternoon. That means crisp air, comfortable conditions in the stands and no major weather factor to blunt the 49ers’ speed or physicality.
On paper, San Francisco enters as a heavy favorite. The 49ers sit at 9–4 and very much in the NFC hunt, while the Titans arrive at Levi’s Stadium at 1–11, struggling through a rebuilding season and facing a brutal road environment. Oddsmakers have installed the 49ers as double-digit favorites, underscoring just how lopsided this matchup appears — but also reinforcing the pressure on San Francisco to handle business at home and avoid a late-season slip.
For 49ers faithful, the message is simple: Sunday afternoon, December 14, FOX, 1:25 p.m. Pacific at Levi’s Stadium. Whether you are in the Bay Area, across the U.S., or following from abroad, the time, TV window and conditions are set. All that remains is for the Niners to turn this primetime-style showcase into another statement performance in front of a roaring home crowd.
