The San Francisco 49ers today announced they have signed OL Brandon Parker to the practice squad. In order to make room on the practice squad, the team released OL Andre Dillard.

Parker (6-8, 320) was originally drafted by the Oakland Raiders in the third round (65th overall) of the 2018 NFL Draft. Throughout his six-year career with the Raiders (2018-23), 49ers (2024-25) and Atlanta Falcons (2024-25) he has appeared in 59 games (33 starts) and started in one postseason contest. Parker signed to the Falcons practice squad on August 27, 2025, was released by the team on September 2, signed to the 49ers practice squad on September 17 before he was released on October 28.

A 30-year-old native of Kannapolis, NC, Parker attended North Carolina Agricultural and Technical State University for five seasons (2013-17) where he started in 48 games. Parker was named the MEAC Offensive Lineman of the Year in consecutive seasons (2015-16) and was a three-time All-MEAC selection (2015-17).

Dillard (6-5, 315) signed to the team’s practice squad on October 28, 2025.